Dr. Martin Luther King, Jr. pens his Letter from Birmingham Jail while incarcerated in Birmingham, Alabama for protesting against segregation.

The police force in Birmingham, Alabama switches tactics and responds with violent force to stop the "Birmingham campaign" protesters. Images of the violent suppression are transmitted worldwide, bringing newfound attention to the African-American Civil Rights Movement.

The 16th Street Baptist Church bombing: Four children killed at an African-American church in Birmingham, Alabama, United States

Southern Airways Flight 49 from Birmingham, Alabama is hijacked and, at one point, is threatened with crashing into the nuclear installation at the Oak Ridge National Laboratory. After two days, the plane lands in Havana, Cuba, where the hijackers are jailed by Fidel Castro.

Walter LeRoy Moody begins his terrorist bombing streak when he sends Judge Robert Smith Vance a bomb in the mail, instantly killing him near his house in Birmingham, Alabama.

In Birmingham, Alabama, a bomb explodes at an abortion clinic, killing one and severely wounding another. Serial bomber Eric Robert Rudolph is suspected as the culprit.

American civil rights movement: a jury in Birmingham, Alabama, convicts former Ku Klux Klan member Bobby Frank Cherry of the 1963 murders of four girls in the bombing of the 16th Street Baptist Church.

FBI agents raid the corporate headquarters of HealthSouth Corporation in Birmingham, Alabama on suspicion of massive corporate fraud led by the company's top executives.