Byzantium is renamed ''Nova Roma'' during a dedication ceremony, but it is more popularly referred to as Constantinople.

Honoratus, the first known Prefect of the City of Constantinople, takes office.

Roman usurper Procopius bribes two legions passing by Constantinople, and proclaims himself Roman emperor.

Theodosius I makes his ''adventus'', or formal entry, into Constantinople.

Valentinian III, Western Roman Emperor, marries Licinia Eudoxia, daughter of his cousin Theodosius II, Eastern Roman Emperor in Constantinople unifying the two branches of the House of Theodosius

Byzantine Emperor Zeno is forced to flee his capital at Constantinople.

Basiliscus becomes Byzantine Emperor, with a coronation ceremony in the Hebdomon palace in Constantinople.

Nika riots in Constantinople.

Nika riots in Constantinople fail.

In Constantinople, the dome of the Hagia Sophia collapses. Justinian I immediately orders that the dome be rebuilt.

The Byzantine church Hagia Sophia in Constantinople is dedicated for the second time after being destroyed by earthquakes.

Heraclius arrives by ship from Africa at Constantinople, overthrows Byzantine Emperor Phocas and becomes Emperor.

The Sixth Ecumenical Council commences in Constantinople.

The Nea Ekklesia is inaugurated in Constantinople, setting the model for all later cross-in-square Orthodox churches.

Alexios I Komnenos is crowned Byzantine emperor at Constantinople, beginning the Komnenian dynasty.

The Fourth Crusade captures Constantinople by assault. The Byzantine emperor Alexius III Angelus flees from his capital into exile.

The Crusaders of the Fourth Crusade breach the walls of Constantinople and enter the city, which they completely occupy the following day.

Constantinople falls to the Crusaders of the Fourth Crusade, temporarily ending the Byzantine Empire.

The city of Constantinople is recaptured by Nicaean forces under the command of Alexios Strategopoulos, re-establishing the Byzantine Empire.

Michael VIII Palaeologus is crowned Byzantine emperor in Constantinople.

Mehmed II begins his siege of Constantinople (Istanbul), which falls on May 29.

Fall of Constantinople: Ottoman armies under Sultan Mehmed II Fatih capture Constantinople after a 53-day siege, ending the Byzantine Empire. Although the date of May 29, 1453 is that of the Julian Calendar, the event is commemorated in Istanbul on this day of the present Gregorian calendar.

AEK Athens FC is established on the anniversary of the siege of Constantinople by the Turks.

Constantinople and Angora change their names to Istanbul and Ankara.