War of 1812: American frigate ''USS Constitution'' defeats the British frigate ''HMS Guerriere'' off the coast of Nova Scotia, Canada earning her nickname "Old Ironsides".

War of 1812: In a naval engagement on Lake Erie, American forces capture two British ships: HMS Detroit and HMS ''Caledonia''.

War of 1812: United States troops capture the capital of Upper Canada, York (present day Toronto, Canada).

War of 1812: In Canada, American forces capture Fort George.

The United States defeats the British Fleet at the Battle of Lake Erie during the War of 1812.

War of 1812: Canadians and Mohawks defeat the Americans in the Battle of Chateauguay.

Americans defeat the British at the Battle of Longwoods between London, Ontario and Thamesville, near present-day Wardsville, Ontario.

War of 1812: In central Alabama, U.S. forces under General Andrew Jackson defeat the Creek at the Battle of Horseshoe Bend.

War of 1812: General Phineas Riall advances toward the Niagara River to halt Jacob Brown's American invaders.

Battle of North Point: an American detachment halts the British land advance to Baltimore in the War of 1812.

New Jersey grants the first American railroad charter to John Stevens.

Opening of the first private mental health hospital in the United States, the Asylum for the Relief of Persons Deprived of the Use of Their Reason (now Friends Hospital) in Philadelphia, Pennsylvania.

At Rome, New York, United States, construction on the Erie Canal begins.

By the Adams-Onís Treaty, Spain sells Florida to the United States for five million U.S. dollars.

The SS Savannah leaves port at Savannah, Georgia, United States, on a voyage to become the first steamship to cross the Atlantic Ocean. The ship arrived at Liverpool, England on June 20.

The Bank of Savings in New York City, the first savings bank in the United States, opens.

Norwich University is founded in Vermont as the first private military school in the United States.

Captain Nathaniel Palmer becomes the first American to see Antarctica (the Palmer Peninsula is later named after him).

The United States takes possession of its newly bought territory of Florida from Spain.

The Florida Territory is created in the United States.

Monroe Doctrine: US President James Monroe delivers a speech establishing American neutrality in future European conflicts.

Freed American slaves found Liberia.

The Creek cede the last of their lands in Georgia to the United States government, and migrate west.

The Baltimore & Ohio Railroad is incorporated, becoming the first railroad in America offering commercial transportation of both people and freight.

U.S. President John Quincy Adams signs the Tariff of 1828 into law, protecting wool manufacturers in the United States.

In the United States, William Austin Burt patents the typographer, a precursor to the typewriter.

The first revenue trains in the United States begin service on the Baltimore and Ohio Railroad between Baltimore, Maryland and Ellicott's Mills, Maryland.

The ''Tom Thumb'' presages the first railway service in the United States.

In Southampton County, Virginia, escaped slave Nat Turner is captured and arrested for leading the bloodiest slave rebellion in United States history.

Indian Wars: The Black Hawk War begins – the Sauk warrior Black Hawk begins a war with the United States.

Black Hawk War: Around three-hundred United States 6th Infantry troops leave St. Louis, Missouri to fight the Sauk Native Americans.

P. T. Barnum and his circus start their first tour of the United States.

The Treaty of New Echota is signed, ceding all the lands of the Cherokee east of the Mississippi River to the United States.

Samuel Colt is granted an United States patent for the Colt revolver.

Battle of Lake Okeechobee: United States forces defeat Seminole Native Americans.

Tennessee enacts the first prohibition law in the United States

Captain Charles Wilkes circumnavigates Antarctica, claiming what became known as Wilkes Land for the United States.

The Great Natchez Tornado strikes Natchez, Mississippi killing 317 people. It is the second deadliest tornado in United States history.

John Greenough is granted the first U.S. patent for the sewing machine.

The Webster-Ashburton Treaty is signed, establishing the United States-Canada border east of the Rocky Mountains.