1229
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12.31.1229
James I of Aragon the Conqueror enters Medina Mayurqa (now known as Palma, Spain) thus consummating the Christian reconquest of the island of Majorca.
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1469
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1483
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1491
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11.25.1491
The siege of Granada, the last Moorish stronghold in Spain, begins.
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1492
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1.2.1492
Reconquista: the emirate of Granada, the last Moorish stronghold in Spain, surrenders
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7.31.1492
The Jews are expelled from Spain when the Alhambra Decree takes effect.
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8.3.1492
The Jews of Spain are expelled by the Catholic Monarchs.
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1493
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1494
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1502
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1503
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4.28.1503
Important victory of the Great captain at the Battle of Cerignola, ruling a small Spanish armies over a French four times bigger in number, in Cerignola, next Bari, Southern Italy. It is noted as the first battle in history won by gunpowder small arms.
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1511
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1513
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4.8.1513
Explorer Juan Ponce de León declares Florida a territory of Spain.
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9.25.1513
Spanish explorer Vasco Núñez de Balboa reaches what would become known as the Pacific Ocean.
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10.7.1513
Battle of La Motta: Spanish troops under Ramón de Cardona defeat the Venetians.
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1516
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1520
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1522
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9.6.1522
The ''Victoria'', the only surviving ship of Ferdinand Magellan's expedition, returns to Sanlúcar de Barrameda in Spain, becoming the first ship to circumnavigate the world.
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1527
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5.6.1527
Spanish and German troops sack Rome; some consider this the end of the Renaissance. 147 Swiss Guards, including their commander, die fighting the forces of Charles V in order to allow Pope Clement VII to escape into Castel Sant'Angelo.
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1528
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11.6.1528
Shipwrecked Spanish conquistador Álvar Núñez Cabeza de Vaca becomes the first known European to set foot in Texas.
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1529
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4.22.1529
Treaty of Saragossa divides the eastern hemisphere between Spain and Portugal along a line 297.5 leagues or 17° east of the Moluccas.
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1533
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11.14.1533
Conquistadors from Spain under the leadership of Francisco Pizarro arrive in Cajamarca, Inca empire
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1536
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1539
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6.3.1539
DeSoto claims Florida for Spain.
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1548
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10.20.1548
The city of Nuestra Senora de La Paz (Our Lady of Peace) was founded by Captain Alonso de Mendoza by appointment of the king of Spain and Holy Roman Emperor, Charles V.
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1556
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1558
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7.13.1558
Battle of Gravelines: in France, Spanish forces led by Count Lamoral of Egmont defeat the French forces of Marshal Paul de Thermes at Gravelines.
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1559
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1565
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1566
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4.5.1566
Two-hundred Dutch noblemen, led by Hendrik van Brederode, force themselves into the presence of Margaret of Parma and present the Petition of Compromise, denouncing the Spanish Inquisition in the Netherlands. The Inquisition is suspended and a delegation is sent to Spain to petition Philip II.
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